Ingredient
PDRN
PDRN (polydeoxyribonucleotide) consists of DNA fragments derived from salmon sperm cells. It works primarily by promoting cell proliferation and suppresses inflammatory pathways. The result is accelerated skin repair, stronger barrier function, and improved elasticity.
Ingredient
Suitable for
Sensitive or post-procedure skin that needs repair
Also suitable for sensitive skin, dry Skin, mature Skin and oily Skin.
Ingredient
Ingredient combination
Combinations that work
- PeptidesRepairing
Both work on repair signalling rather than exfoliation: PDRN supports tissue recovery, peptides signal for collagen. Neither needs a low pH, so they layer in the same step without interfering.
- Hyaluronic AcidHydrating
PDRN works on repair signalling and needs a hydrated surface to do it. Hyaluronic acid layered underneath keeps the skin in that state — the standard base for a PDRN serum.
- Centella AsiaticaCalming
PDRN supports repair; centella lowers the inflammation that slows it. Neither needs a low pH, so they can be layered in the same routine without waiting between them.
Combinations to avoid
PDRN has no documented conflicts with anything else in this library. It can sit anywhere in a routine.
Routine
Routines with PDRN
Routines featuring this ingredient are coming soon.